Roasted Aconite Lateral Root … Safety & Interactions

Pao Fu Zi · Aconiti Lateralis Radix Praeparata

Contraindications

  • Pregnancy
  • Heat syndromes, Yin deficiency with heat, or true fluid depletion without cold
  • Raw, under-processed, or under-decocted aconite for internal use
  • Known ventricular arrhythmia or unstable severe cardiac disease without expert supervision

Cautions

  • Pao Fu Zi remains highly toxic despite processing and should only be used as an authenticated prepared product under experienced supervision.
  • Pre-decoction is standard because inadequate cooking leaves dangerous diester alkaloids active.
  • Early poisoning can present with oral numbness, tingling, nausea, vomiting, diarrhea, weakness, hypotension, and life-threatening ventricular arrhythmias.

Drug Interactions

Drug Class / Substrate Mechanism Severity Source
Cardiac glycosides such as digoxin ... additive arrhythmogenic risk
Class I and III antiarrhythmic drugs ... unpredictable electrophysiologic interaction
Beta-blockers or other rate-slowing agents ... may worsen bradycardia or mask early toxicity
QT-prolonging medications ... additive risk of malignant ventricular arrhythmia

Pregnancy

Not recommended during pregnancy. Consult a qualified practitioner before any use.

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before using herbal medicines, especially if you take prescription medications.