Snake Slough

Chinese
蛇蜕
Pinyin
She Tui
Latin
Periostracum Serpentis
Scientific specimen plate of Snake Slough, Periostracum Serpentis, showing shed skin forms and diagnostic specimen details.
Botanical plate by Kodi .

Known in TCM as She Tui (蛇蜕), this sweet and salty, neutral herb enters the Liver. Traditionally, it dispels wind and stops spasms or convulsions in childhood or febrile-wind traditions, most often applied for epilepsy, conjunctivitis, and sore throat. Modern research has identified Keratinous among its active constituents.

Part used: Shed skin

Also Known As

She Tui Pi Snake shed skin

Latin: Periostracum Serpentis | Pinyin: She Tui | Chinese: 蛇蜕

TCM Properties

Taste
sweet, salty
Temperature
neutral
Channels
Liver

Traditional Use

Primary Actions

  • Dispels wind and stops spasms or convulsions in childhood or febrile-wind traditions.
  • Brightens the eyes and removes superficial obstruction, especially for red eyes or corneal opacity-style complaints.
  • Resolves swelling and attacks toxin in sore throat, chronic sores, scrofula, and localized inflammatory conditions.
  • Relieves itching and helps with skin conditions involving wind or parasite irritation.

Secondary Actions

  • She Tui is the sloughed skin layer, not snake flesh or bile, and its traditional profile is correspondingly lighter and more surface-oriented.
  • This page stays conservative because direct modern indexed literature on the classical medicinal itself is thin compared with the strength of traditional use.

Classic Formulas

  • Wind-spasm and childhood convulsion combinations ... the traditional internal calming lane.
  • Eye and throat pairings for corneal film or sore throat ... the upper-orifice use context.
  • Topical toxin-attacking combinations with Lu Feng Fang or Feng Fang ... older skin and sore practice.

Classical References

  • Traditional herbology describes She Tui as sweet, salty, and neutral, entering the Liver to dispel wind and benefit the eyes.
  • Its classic indications extend to convulsions, sore throat, skin itching, and chronic toxic swellings.
  • The slough is valued for a light, penetrating quality that acts on the surface, channels, and upper orifices.

Modern Research

Active Compounds

  • Keratinous shed-skin matrix and associated bioactive fractions
  • Authentication markers relevant to snake-derived medicinal materials

Studied Effects

  • A 2013 study on Naja naja shed-skin extract found measurable reproductive and inflammatory effects in mice, which confirms biologic activity and supports a cautious safety posture for snake-slough materials (PMID 23678544).
  • A 2017 review on molecular identification of snake drugs is important context because market authentication remains a major issue for snake-derived medicinals including shed skin (PMID 29139259).
  • The broader 2003 review of animal products in traditional Chinese medicine remains relevant here for environmental, legal, and health-hazard context around historical animal materials (PMID 12801499).

PubMed References

Safety & Interactions

Contraindications

  • Pregnancy
  • Use of poorly sourced or contaminated shed-skin material

Cautions

  • Snake slough is an animal-derived medicinal with limited direct clinical evidence and should not be improvised from non-medicinal shed skins.
  • The available animal study suggests biologic effects on reproductive signaling, so pregnancy caution is appropriate.

Conditions

Frequently Asked Questions

What is Snake Slough used for?

Snake Slough is traditionally used to Dispels wind and stops spasms or convulsions in childhood or febrile-wind traditions., Brightens the eyes and removes superficial obstruction, especially for red eyes or corneal opacity-style complaints., Resolves swelling and attacks toxin in sore throat, chronic sores, scrofula, and localized inflammatory conditions., Relieves itching and helps with skin conditions involving wind or parasite irritation.. Research has investigated its effects on: A 2013 study on Naja naja shed-skin extract found measurable reproductive and inflammatory effects in mice, which confirms biologic activity and supports a cautious safety posture for snake-slough materials (PMID 23678544).; A 2017 review on molecular identification of snake drugs is important context because market authentication remains a major issue for snake-derived medicinals including shed skin (PMID 29139259)..

What are other names for Snake Slough?

Snake Slough is also known as She Tui Pi, Snake shed skin. In TCM: 蛇蜕 (She Tui); Periostracum Serpentis.

Is Snake Slough safe during pregnancy?

Snake Slough is not recommended during pregnancy. The available animal study suggests biologic effects on reproductive signaling, so pregnancy caution is appropriate.

What are the contraindications for Snake Slough?

Snake Slough should not be used in: Pregnancy; Use of poorly sourced or contaminated shed-skin material. Consult a qualified practitioner before use.