Rhizome of Radde Anemone

Pinyin
Zhu Jie Xiang Fu
Latin
Rhizoma Anemones Raddeanae
Botanical illustration of Rhizome of Radde Anemone, Anemone raddeana, showing Zhu Jie Xiang Fu trade rhizome material and diagnostic source details.
Botanical plate by Kodi .

This pungent, hot herb enters the Spleen. Traditionally, it dispels wind-damp and relieves stubborn joint pain ... Zhu Jie Xiang Fu is used for cold-damp obstruction, aching limbs, and painful joints with a resistant quality, most often applied for rheumatism, joint pain, and abscess. Modern research has identified Raddeanin among its active constituents.

Part used: Rhizome

Also Known As

Zhu Jie Xiang Fu Anemone raddeana Rhizome Trade Anemone Rhizome

Latin: Rhizoma Anemones Raddeanae | Pinyin: Zhu Jie Xiang Fu

TCM Properties

Taste
pungent
Temperature
hot
Channels
Spleen

Traditional Use

Primary Actions

  • Dispels wind-damp and relieves stubborn joint pain ... Zhu Jie Xiang Fu is used for cold-damp obstruction, aching limbs, and painful joints with a resistant quality.
  • Reduces swelling and relieves fixed obstructive pain ... traditional use includes painful swellings, neuralgia-type discomfort, and hard obstructive soreness.
  • Resolves toxic swellings in the broader Anemone raddeana tradition ... older use extends to boils, carbuncles, and inflamed lesions where a hot toxic rhizome was chosen.

Secondary Actions

  • This page follows the trade-rhizome-forward Zhu Jie Xiang Fu naming lane of Anemone raddeana rather than the more classical Liang Tou Jian naming kept in `radde-anemone-rhizome`.
  • The hot toxic profile matters ... modern antitumor interest does not make this a casual pain or cancer herb.

Classic Formulas

  • Wind-damp pain combinations pair Zhu Jie Xiang Fu with Qin Jiao or Wei Ling Xian when cold obstruction and joint pain dominate.
  • Swelling and fixed-pain patterns combine it with Ru Xiang or Mo Yao when the goal is to break resistant painful accumulations.
  • Toxic-swelling folk combinations pair it with Jin Yin Hua or Pu Gong Ying when hot swollen lesions are prominent.

Classical References

  • Traditional sources on Anemone raddeana describe the rhizome as pungent, hot, and toxic, used mainly for wind-damp pain and swelling.
  • The clinical distinction from Liang Tou Jian here is mostly naming emphasis and trade presentation, not a different species or radically different pharmacology.

Modern Research

Active Compounds

  • Raddeanin A and related triterpenoid saponins ... the best-known modern constituents
  • Oleanane-type pentacyclic triterpenoids ... a major structural family in Anemone raddeana rhizome
  • Lupeol, betulin, and betulinic-acid derivatives ... supportive anti-inflammatory and cytotoxic fractions

Studied Effects

  • A 2018 review summarized the chemistry and pharmacological effects of Anemone raddeana rhizome and confirmed its longstanding use for neuralgia and rheumatism (PMID 28986812).
  • A 2018 analytical study profiled cytotoxic triterpenoids in the rhizomes of Anemone raddeana, underscoring how strongly the modern literature focuses on saponin chemistry and antitumor potential (PMID 29976404).
  • A 2020 cell-based study reported anti-breast-cancer activity alongside toxicity observations for total secondary saponins from Anemone raddeana rhizome, reinforcing both pharmacologic interest and the need for caution (PMID 32446927).

PubMed References

Safety & Interactions

Contraindications

  • Pregnancy
  • Yin-deficient heat patterns
  • Weak constitution with poor tolerance for hot toxic herbs

Cautions

  • Zhu Jie Xiang Fu is traditionally classed as toxic and should not be treated as a casual daily anti-inflammatory or antitumor supplement.
  • Modern cytotoxic and saponin-rich literature may explain pharmacologic activity, but it also strengthens the case for supervision rather than self-treatment.

Conditions

Frequently Asked Questions

What is Rhizome of Radde Anemone used for?

Rhizome of Radde Anemone is traditionally used to Dispels wind-damp and relieves stubborn joint pain ... Zhu Jie Xiang Fu is used for cold-damp obstruction, aching limbs, and painful joints with a resistant quality., Reduces swelling and relieves fixed obstructive pain ... traditional use includes painful swellings, neuralgia-type discomfort, and hard obstructive soreness., Resolves toxic swellings in the broader Anemone raddeana tradition ... older use extends to boils, carbuncles, and inflamed lesions where a hot toxic rhizome was chosen.. Research has investigated its effects on: A 2018 review summarized the chemistry and pharmacological effects of Anemone raddeana rhizome and confirmed its longstanding use for neuralgia and rheumatism (PMID 28986812).; A 2018 analytical study profiled cytotoxic triterpenoids in the rhizomes of Anemone raddeana, underscoring how strongly the modern literature focuses on saponin chemistry and antitumor potential (PMID 29976404)..

What are other names for Rhizome of Radde Anemone?

Rhizome of Radde Anemone is also known as Zhu Jie Xiang Fu, Anemone raddeana Rhizome, Trade Anemone Rhizome. In TCM: Rhizoma Anemones Raddeanae.

Is Rhizome of Radde Anemone safe during pregnancy?

Rhizome of Radde Anemone is not recommended during pregnancy.

What are the contraindications for Rhizome of Radde Anemone?

Rhizome of Radde Anemone should not be used in: Pregnancy; Yin-deficient heat patterns; Weak constitution with poor tolerance for hot toxic herbs. Consult a qualified practitioner before use.