Natural Herb Library

Rhizome Of Hypoglaucous Collett Yam

Pinyin
Bi Xie
Latin
Rhizoma Dioscoreae Hypoglaucae
Botanical illustration of Rhizome of Hypoglaucous Collett Yam, Dioscorea collettii var. hypoglauca, showing medicinal Bi Xie rhizome sections and diagnostic source details.
Botanical plate by Kodi .

This bitter, neutral herb enters the Kidney and Stomach. Traditionally, it separates the clear from the turbid and drains dampness ... Bi Xie is classically used for cloudy urine, white turbidity, and persistent damp leukorrhea, most often applied for leukorrhea, frequent urination, and rheumatism. Modern research has identified Steroidal among its active constituents.

Part used: Rhizome

Also Known As

Bi Xie Dioscorea collettii var. hypoglauca Rhizome Trade Bi Xie Rhizome

Latin: Rhizoma Dioscoreae Hypoglaucae | Pinyin: Bi Xie

TCM Properties

Taste
bitter
Temperature
neutral
Channels
Kidney, Stomach

Traditional Use

Primary Actions

  • Separates the clear from the turbid and drains dampness ... Bi Xie is classically used for cloudy urine, white turbidity, and persistent damp leukorrhea.
  • Dispels wind-damp and relieves painful obstruction ... it is used for swollen, heavy, or fixed joint pain when dampness is prominent.
  • Helps resolve damp-toxic skin patterns ... traditional use extends to moist eczema, damp sores, and lower-burner turbidity with skin involvement.

Secondary Actions

  • This page should stay distinct from the already-live `hypoglaucous-collett-yam-rhizome` Fen Bi Xie sibling ... same medicinal family, but this record follows the broader trade Bi Xie lane rather than the specifically powder-form identity.
  • The core clinical idea is cloudy turbidity with damp obstruction, not simple dry urinary irritation.

Classic Formulas

  • Bi Xie Fen Qing Yin ... classic formula context for cloudy urine and lower-burner turbidity in which Bi Xie is the signature herb.
  • Bi Xie with Yi Zhi Ren and Shi Chang Pu ... pairing logic for frequent cloudy urination with deficiency and damp obstruction together.
  • Bi Xie with Huang Bai, Fang Ji, or Ren Dong Teng ... damp-heat or painful-obstruction strategy when urinary turbidity overlaps with swollen painful joints.

Classical References

  • Traditional herbology describes Bi Xie as bitter and neutral, entering the Kidney and Stomach to separate the clear from the turbid and relieve damp painful obstruction.
  • Because several species circulate under the Bi Xie name, identity control matters and this page should not erase the distinction from Fen Bi Xie or Mian Bi Xie lanes.

Modern Research

Active Compounds

  • Steroidal saponins including dioscin and related sapogenins ... the best-known modern candidates in Bi Xie pharmacology
  • Diosgenin-forming saponin fractions ... frequently discussed in anti-inflammatory and uric-acid research
  • Tannins and starch ... supportive traditional crude-drug constituents

Studied Effects

  • A 2021 study found that total saponins of Dioscorea collettii attenuated monosodium urate crystal-induced inflammation through suppression of TLR4/NF-kappaB signaling, supporting the gout and damp-bi research bridge around Bi Xie materials (PMID 34721647).
  • An earlier experimental paper reported that total saponins of Dioscorea improved hyperuricemia-related parameters in animal models, reinforcing the species group's modern uric-acid interest (PMID 16437741).
  • A 2016 rat study showed that total saponins from Dioscorea septemloba lowered serum uric acid through transporter regulation, which is useful comparative evidence but still not direct human proof for this exact Bi Xie trade lane (PMID 27072969).

PubMed References

Safety & Interactions

Contraindications

  • Marked yin deficiency with dryness and depletion rather than damp turbidity

Cautions

  • Bi Xie is drying enough that long-term use can be a poor fit for people with pronounced fluid deficiency.
  • Several different species circulate under the Bi Xie name, so substitution and identity confusion are real concerns.
  • Most of the gout and hyperuricemia literature remains preclinical or species-group based rather than direct clinical evidence for this exact crude drug.

Conditions

Frequently Asked Questions

What is Rhizome Of Hypoglaucous Collett Yam used for?

Rhizome Of Hypoglaucous Collett Yam is traditionally used to Separates the clear from the turbid and drains dampness ... Bi Xie is classically used for cloudy urine, white turbidity, and persistent damp leukorrhea., Dispels wind-damp and relieves painful obstruction ... it is used for swollen, heavy, or fixed joint pain when dampness is prominent., Helps resolve damp-toxic skin patterns ... traditional use extends to moist eczema, damp sores, and lower-burner turbidity with skin involvement.. Research has investigated its effects on: A 2021 study found that total saponins of Dioscorea collettii attenuated monosodium urate crystal-induced inflammation through suppression of TLR4/NF-kappaB signaling, supporting the gout and damp-bi research bridge around Bi Xie materials (PMID 34721647).; An earlier experimental paper reported that total saponins of Dioscorea improved hyperuricemia-related parameters in animal models, reinforcing the species group's modern uric-acid interest (PMID 16437741)..

What are other names for Rhizome Of Hypoglaucous Collett Yam?

Rhizome Of Hypoglaucous Collett Yam is also known as Bi Xie, Dioscorea collettii var. hypoglauca Rhizome, Trade Bi Xie Rhizome. In TCM: Rhizoma Dioscoreae Hypoglaucae.

Is Rhizome Of Hypoglaucous Collett Yam safe during pregnancy?

The safety of Rhizome Of Hypoglaucous Collett Yam during pregnancy has not been established. Consult a qualified healthcare provider before use.

What are the contraindications for Rhizome Of Hypoglaucous Collett Yam?

Rhizome Of Hypoglaucous Collett Yam should not be used in: Marked yin deficiency with dryness and depletion rather than damp turbidity. Consult a qualified practitioner before use.