Peking Euphorbia Root … Safety & Interactions

Jing Da Ji · Radix Euphorbiae Pekinensis

Contraindications

  • Pregnancy (traditionally recognized as an abortifacient)
  • Breastfeeding
  • Weak or frail patients

Cautions

  • Extremely toxic; irritates the gastrointestinal tract and skin
  • Vinegar processing reduces toxicity and is standard before use
  • Do not combine with Gan Cao (Licorice); animal studies show this combination increases Da Ji's toxicity
  • Not for prolonged use

Drug Interactions

Drug Class / Substrate Mechanism Severity Source
Contraindicated in combination with Gan Cao (Glycyrrhiza uralensis / Licorice), per the classical "eighteen incompatible medicaments" tradition, confirmed by modern toxicity studies

Pregnancy

Not recommended during pregnancy. Consult a qualified practitioner before any use.

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before using herbal medicines, especially if you take prescription medications.