Pearl

Chinese
珍珠
Pinyin
Zhen Zhu
Latin
Margarita
Scientific specimen plate of Pearl, Margarita, showing whole pearls, cut sections, powder, and diagnostic pearl details.
Botanical plate by Kodi .

Known in TCM as Zhen Zhu (珍珠), this sweet and salty, cold herb enters the Heart and Liver. Traditionally, it calms the Spirit and anchors the Heart; treats both Excess-type Shen disturbance (tremors, seizures, childhood convulsions) and Deficiency-type Shen disturbance (insomnia, palpitations, being easily frightened), most often applied for insomnia, epilepsy, and blurred vision. Modern research has identified Calcium among its active constituents.

Part used: Pearl

Also Known As

Pteria martensii pearl Freshwater Pearl

Latin: Margarita | Pinyin: Zhen Zhu | Chinese: 珍珠

TCM Properties

Taste
sweet, salty
Temperature
cold
Channels
Heart, Liver

Traditional Use

Primary Actions

  • Calms the Spirit and anchors the Heart; treats both Excess-type Shen disturbance (tremors, seizures, childhood convulsions) and Deficiency-type Shen disturbance (insomnia, palpitations, being easily frightened)
  • Clears Liver Fire and removes superficial visual obstruction, brightening the eyes
  • Promotes tissue regeneration; applied topically for non-healing skin ulcers, often combined with Bing Pian and Ru Xiang

Secondary Actions

  • More strongly Heart-calming than Zhen Zhu Mu (Mother of Pearl/Nacre), which more effectively calms the Liver

Classical References

  • Documented in later Chinese materia medica as a precious calming substance for both Excess Wind-type and Deficiency-type Spirit disturbance

Modern Research

Active Compounds

  • Calcium carbonate (aragonite)
  • Conchiolin protein matrix
  • Trace amino acids

Studied Effects

  • Pearl powder stimulates fibroblast proliferation, migration, and collagen deposition, accelerating wound healing in vitro and in vivo
  • Nanoscale pearl powder formulations show the highest wound-healing efficiency among tested particle sizes
  • Traditional use for aphthous, gastric, and duodenal ulcers is consistent with documented tissue-regenerative activity

PubMed References

Safety & Interactions

Cautions

  • Must be finely powdered (levigated) before use
  • Source from quality-controlled suppliers given general heavy-metal contamination risk documented across mineral and shell Chinese medicinals
  • Spleen-Stomach Deficiency Cold

Conditions

Frequently Asked Questions

What is Pearl used for?

Pearl is traditionally used to Calms the Spirit and anchors the Heart; treats both Excess-type Shen disturbance (tremors, seizures, childhood convulsions) and Deficiency-type Shen disturbance (insomnia, palpitations, being easily frightened), Clears Liver Fire and removes superficial visual obstruction, brightening the eyes, Promotes tissue regeneration; applied topically for non-healing skin ulcers, often combined with Bing Pian and Ru Xiang. Research has investigated its effects on: Pearl powder stimulates fibroblast proliferation, migration, and collagen deposition, accelerating wound healing in vitro and in vivo; Nanoscale pearl powder formulations show the highest wound-healing efficiency among tested particle sizes.

What are other names for Pearl?

Pearl is also known as Pteria martensii pearl, Freshwater Pearl. In TCM: 珍珠 (Zhen Zhu); Margarita.

Is Pearl safe during pregnancy?

The safety of Pearl during pregnancy has not been established. Consult a qualified healthcare provider before use.