Nux Vomica Powder (Processed)

Chinese
马钱子粉
Pinyin
Ma Qian Zi Fen
Latin
Semen Strychni Pulveratum
Scientific specimen plate of Nux Vomica Powder, Strychnos nux-vomica, showing powdered seed material and diagnostic powder details.
Botanical plate by Kodi .

Known in TCM as Ma Qian Zi Fen (马钱子粉), this bitter, warm herb enters the Liver and Spleen. Traditionally, it the finely milled, pharmacopoeia-standardized powder form of processed Ma Qian Zi, formulated to a specified strychnine content for precise, minimal dosing, most often applied for joint pain and traumatic injury. Modern research has identified Strychnine among its active constituents.

Part used: Seed

Also Known As

Standardized Nux Vomica Powder Processed Strychnos nux-vomica powder

Latin: Semen Strychni Pulveratum | Pinyin: Ma Qian Zi Fen | Chinese: 马钱子粉

TCM Properties

Taste
bitter
Temperature
warm
Channels
Liver, Spleen

Traditional Use

Primary Actions

  • The finely milled, pharmacopoeia-standardized powder form of processed Ma Qian Zi, formulated to a specified strychnine content for precise, minimal dosing
  • Unblocks the channels and relieves pain in Bi syndrome and traumatic injury, used only in milligram-level doses

Classical References

  • The Chinese Pharmacopoeia specifies a standardized strychnine content range for this powder form specifically to enable safer, more precise dosing than crude processed seed

Modern Research

Active Compounds

  • Strychnine (standardized content)
  • Brucine

Studied Effects

  • Standardized powder formulation allows tighter dose control than crushed processed seed, reducing the risk of inadvertent overdose
  • Retains the anti-inflammatory and analgesic alkaloid activity documented for Nux Vomica total alkaloid extracts

PubMed References

Safety & Interactions

Contraindications

  • Pregnancy
  • Children
  • Cardiac conduction disorders
  • Self-administration without a pharmacopoeia-compliant, practitioner-supervised protocol

Cautions

  • Even at standardized dosing, this remains one of the most toxic substances in regular Chinese Pharmacopoeia use; strict adherence to specified milligram dosing is essential
  • Overdose causes convulsions and can be fatal

Drug Interactions

  • Contraindicated in combination with other CNS stimulants or medications lowering seizure threshold

Conditions

Frequently Asked Questions

What is Nux Vomica Powder (Processed) used for?

Nux Vomica Powder (Processed) is traditionally used to The finely milled, pharmacopoeia-standardized powder form of processed Ma Qian Zi, formulated to a specified strychnine content for precise, minimal dosing, Unblocks the channels and relieves pain in Bi syndrome and traumatic injury, used only in milligram-level doses. Research has investigated its effects on: Standardized powder formulation allows tighter dose control than crushed processed seed, reducing the risk of inadvertent overdose; Retains the anti-inflammatory and analgesic alkaloid activity documented for Nux Vomica total alkaloid extracts.

What are other names for Nux Vomica Powder (Processed)?

Nux Vomica Powder (Processed) is also known as Standardized Nux Vomica Powder, Processed Strychnos nux-vomica powder. In TCM: 马钱子粉 (Ma Qian Zi Fen); Semen Strychni Pulveratum.

Is Nux Vomica Powder (Processed) safe during pregnancy?

Nux Vomica Powder (Processed) is not recommended during pregnancy.

What are the contraindications for Nux Vomica Powder (Processed)?

Nux Vomica Powder (Processed) should not be used in: Pregnancy; Children; Cardiac conduction disorders; Self-administration without a pharmacopoeia-compliant, practitioner-supervised protocol. Consult a qualified practitioner before use.

Does Nux Vomica Powder (Processed) interact with any medications?

Nux Vomica Powder (Processed) may interact with: Contraindicated in combination with other CNS stimulants or medications lowering seizure threshold. Always inform your healthcare provider of any herbal supplements you are taking.