Muskmelon Seed

Chinese
甜瓜子
Pinyin
Tian Gua Zi
Latin
Semen Cucumis
Botanical illustration of Muskmelon Seed, Cucumis melo, showing seed cavity, flat pale seeds, dried Tian Gua Zi seeds, and diagnostic seed details.
Botanical plate by Kodi .

Known in TCM as Tian Gua Zi (甜瓜子), this sweet, cold herb enters the Lung, Stomach, and Large Intestine. Traditionally, it clears Lung Heat and moistens the Intestines; treats cough from Lung Heat and constipation from dryness, most often applied for cough, constipation, and appendicitis. Modern research has identified Fatty among its active constituents.

Part used: Seed

Also Known As

Semen Melo Cucumis melo seed

Latin: Semen Cucumis | Pinyin: Tian Gua Zi | Chinese: 甜瓜子

TCM Properties

Taste
sweet
Temperature
cold
Channels
Lung, Stomach, Large Intestine

Traditional Use

Primary Actions

  • Clears Lung Heat and moistens the Intestines; treats cough from Lung Heat and constipation from dryness
  • Dissipates Blood stasis and expels pus; used for pulmonary abscess and intestinal abscess (acute appendicitis)

Secondary Actions

  • Also used topically and internally to heal wounds and relieve pain from traumatic injury and fracture

Classical References

  • Distinguished from the toxic Gua Di (melon pedicel) as the non-toxic seed of the same plant, used for moistening and pus-expelling rather than emetic purposes

Modern Research

Active Compounds

  • Fatty acids
  • Cucurbitacins (trace)
  • Polyphenols

Studied Effects

  • Anti-inflammatory, anticancer, antibacterial, hepatoprotective, and immunomodulatory activity documented across seed and whole-fruit extracts
  • Supports traditional pus-expelling and wound-healing use

PubMed References

Safety & Interactions

Contraindications

  • Diarrhea
  • Spleen-Stomach Deficiency Cold

Conditions

Frequently Asked Questions

What is Muskmelon Seed used for?

Muskmelon Seed is traditionally used to Clears Lung Heat and moistens the Intestines; treats cough from Lung Heat and constipation from dryness, Dissipates Blood stasis and expels pus; used for pulmonary abscess and intestinal abscess (acute appendicitis). Research has investigated its effects on: Anti-inflammatory, anticancer, antibacterial, hepatoprotective, and immunomodulatory activity documented across seed and whole-fruit extracts; Supports traditional pus-expelling and wound-healing use.

What are other names for Muskmelon Seed?

Muskmelon Seed is also known as Semen Melo, Cucumis melo seed. In TCM: 甜瓜子 (Tian Gua Zi); Semen Cucumis.

Is Muskmelon Seed safe during pregnancy?

Muskmelon Seed is generally considered safe during pregnancy in normal amounts. Therapeutic or concentrated doses should be discussed with a qualified practitioner before use.

What are the contraindications for Muskmelon Seed?

Muskmelon Seed should not be used in: Diarrhea; Spleen-Stomach Deficiency Cold. Consult a qualified practitioner before use.