Matrine … Safety & Interactions
Ku Shen Jian · Matrinum
Contraindicated / High risk. Use only under practitioner supervision.
Contraindications
- Pregnancy
- Pre-existing liver impairment
Cautions
- Documented hepatotoxicity and neurotoxicity at high or prolonged dosing; use only under practitioner and, where applicable, medical supervision
- Not equivalent in dosing or safety profile to whole Ku Shen root; purified alkaloid forms carry a narrower margin of safety
Drug Interactions
| Drug Class / Substrate | Mechanism | Severity | Source |
|---|---|---|---|
| Theoretical additive hepatotoxic risk with other liver-metabolized medications | |||
Pregnancy
Not recommended during pregnancy. Consult a qualified practitioner before any use.
This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before using herbal medicines, especially if you take prescription medications.