A maca and losartan interaction has been observed in hypertensive rats, but clinical relevance is not known. The larger concerns are limited medication data, possible hormone-related effects, and interference with testosterone laboratory testing.

Use with caution. Healthcare professional review recommended before use.

Contraindications

Pregnancy or breastfeeding without medical guidance
Hormone-sensitive breast or uterine cancer without oncology review

Cautions

Human safety data remain limited despite maca's history as a food.
Altered menstrual cycles, insomnia, gastritis, and mood changes have been reported.
Maca may interfere with testosterone immunoassays.

Drug Interactions

Drug Class / Substrate	Mechanism	Severity	Source
Losartan and possibly other blood pressure medicines	Maca enhanced losartan's blood-pressure-lowering effect in rats. Human relevance is not known.	Uncertain	Memorial Sloan Kettering About Herbs

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before using herbal medicines, especially if you take prescription medications.