Lepidium Seed, Descurainia Seed … Safety & Interactions

Ting Li Zi · Semen Lepidii seu Descurainiae

Contraindications

  • Qi deficiency or weak constitution without obvious excess phlegm-fluid accumulation
  • Pregnancy unless specifically supervised

Cautions

  • Ting Li Zi is a harsh draining seed that can injure qi and the middle burner if used too long or in deficiency patients.
  • Modern literature suggests possible effects on drug-metabolizing enzymes and P-glycoprotein, so concentrated extracts deserve extra medication-review caution.
  • Some modern sources also note cardiac-glycoside-like activity in Ting Li Zi traditions, which supports keeping the dosing and indication frame conservative.

Drug Interactions

Drug Class / Substrate Mechanism Severity Source
Potential interaction with CYP- or UGT-metabolized drugs based on in vitro enzyme studies.
Potential interaction with P-glycoprotein substrate drugs based on in vitro transporter studies.

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before using herbal medicines, especially if you take prescription medications.