Korean Ginseng … Safety & Interactions

Gao Li Shen · Ginseng Coreensis Radix

Contraindications

  • Acute excess heat or agitation without deficiency
  • Concurrent warfarin therapy without close monitoring
  • Marked stimulant-type insomnia, palpitations, or uncontrolled hypertension with clear excess signs

Cautions

  • Memorial Sloan Kettering lists interaction concerns for Asian ginseng with warfarin, insulin, imatinib, and raltegravir, and that guidance is relevant here because Gao Li Shen remains a Panax ginseng product.
  • Because Korean ginseng in commerce may refer to source, grade, or processing status, it should not automatically be treated as identical to fresh Ren Shen or later Hong Shen preparations.
  • High-dose use may cause insomnia, nervousness, blood-pressure changes, or gastrointestinal upset.

Drug Interactions

Drug Class / Substrate Mechanism Severity Source
Warfarin - possible change in anticoagulant effect or bleeding risk.
Insulin or hypoglycemic drugs - possible additive glucose-lowering effect.
Imatinib or raltegravir - potential increase in liver injury risk noted by MSK.

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before using herbal medicines, especially if you take prescription medications.