Henbane Seed … Safety & Interactions
Tian Xian Zi · Hyoscyamii Semen
Contraindicated / High risk. Use only under practitioner supervision.
Contraindications
- Pregnancy
- Children or unsupervised home use
- Heart disease, tachyarrhythmia, glaucoma, or urinary retention-prone states
- Any repeated or prolonged internal dosing without expert supervision
Cautions
- Tian Xian Zi is highly toxic and can cause anticholinergic poisoning with delirium, dry mouth, dilated pupils, hyperthermia, rapid pulse, urinary retention, seizures, and coma.
- Official Chinese references explicitly warn against overdose and against continuous use even when the herb is being used medicinally.
- Its dramatic historical analgesic and antispasmodic reputation does not make it an acceptable everyday cough, pain, or diarrhea remedy.
Drug Interactions
| Drug Class / Substrate | Mechanism | Severity | Source |
|---|---|---|---|
| Other anticholinergic drugs - possible additive toxicity with atropine-like effects. | |||
| Sedative or centrally acting drugs - may unpredictably intensify neurologic adverse effects. | |||
Pregnancy
Not recommended during pregnancy. Consult a qualified practitioner before any use.
This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before using herbal medicines, especially if you take prescription medications.