Water Buffalo Horn Classic Formulas

Primary Actions

Clears Heat and cools the Blood - used for high fever, crimson tongue, agitation, purple rashes, and bleeding disorders when warm-pathogen heat has entered the nutritive or Blood level.
Stops reckless movement of Blood - classically used for epistaxis, hematemesis, blood in the stool or urine, and other bleeding presentations caused by intense Blood Heat rather than deficiency or trauma.
Resolves toxicity - applied when severe Heat toxins produce dark eruptions, swollen painful throat, or ulcerative hot lesions reflecting deep febrile toxicity.
Calms the spirit and arrests tremors - used for febrile convulsions, delirium, mania, or heat-induced loss of consciousness when blazing Heat disturbs the Heart and Liver.

Xi Jiao Di Huang Tang (犀角地黄汤) - in modern practice Shui Niu Jiao replaces the prohibited Xi Jiao to cool Blood-level heat, stop reckless bleeding, and address dark eruptions, delirium, and severe febrile toxicity.
Qing Ying Tang (清营汤) - a warm-disease formula for nutritive-level Heat with high fever, nighttime agitation, and early delirium, where Shui Niu Jiao clears deep heat from the Heart-nutritive level.
Zhi Bao Dan (至宝丹) - major orifice-opening emergency formula in which Shui Niu Jiao helps clear heat from the Blood and Pericardium while supporting the restoration of consciousness.
An Gong Niu Huang Wan (安宫牛黄丸) - modern versions use Shui Niu Jiao in place of Xi Jiao for severe heat-closing patterns with high fever, convulsions, coma, and toxic inflammation.

Me & Qi identifies Shui Niu Jiao as bitter, salty, and cold, entering the Heart, Liver, and Stomach to cool Blood, resolve toxicity, calm the spirit, and stop heat-driven bleeding or convulsions.
MODERN SUBSTITUTE NOTE: Me & Qi explicitly describes Shui Niu Jiao as the modern replacement for the now-banned rhinoceros horn Xi Jiao, generally used at roughly ten times the original dosage.
Classical incompatibility traditions place Shui Niu Jiao in the substitute position for Xi Jiao among the Nineteen Mutual Fears, so caution is advised with Chuan Wu, Cao Wu, and Fu Zi even though the modern substitute is described as a milder, mutually diminishing pairing rather than a direct toxic combination.