Contraindicated / High risk. Use only under practitioner supervision.
TCM Properties
- Taste
- sweet, salty
- Temperature
- cool
- Channels
- Lung, Stomach
Traditional Use
Primary Actions
- Clears Heat and resolves toxicity for external use - classically applied to sore throat, swollen painful tonsils, aphthous ulcers, gum erosion, and oral lesions where heat toxin and swelling are prominent.
- Promotes tissue regeneration and prevents putrefaction - especially in calcined form for chronic sores, ulcerated tissue, and lesions that need both antiseptic drying and healing support.
- Clears Lung Heat and transforms phlegm - a secondary internal use for productive cough with thick yellow sputum, especially when throat swelling or toxin-heat accompanies the phlegm.
- Brightens the eyes and removes superficial visual obstructions - used in eye washes or powders for red painful eyes, corneal nebulae, and heat-type conjunctival irritation.
Secondary Actions
- Raw Peng Sha emphasizes clearing heat-toxin and dissolving putrescence, while calcined Duan Peng Sha is more astringent and is preferred for drying weeping lesions and promoting closure.
- Modern practice overwhelmingly favors external application because internal use has a narrow safety window and cumulative toxicity.
Classic Formulas
- Bing Peng San (冰硼散) - from Wai Ke Zheng Zong, a classic topical powder with Bing Pian, Xuan Ming Fen, and traditionally Zhu Sha for sore throat, mouth ulcers, gum pain, and heat-toxic oral lesions.
- Yu Yao Shi (玉钥匙) - classical throat-opening powder traditions use Peng Sha as a leading ingredient for severe wind-heat throat obstruction, swelling, and phlegm blocking the throat.
- Bai Long Dan (白龙丹) - classical ophthalmic powder traditions combine Peng Sha with Bing Pian, Lu Gan Shi, and related eye-clearing substances for red swollen painful eyes and superficial corneal opacity.
Classical References
- IMPORT NOTE: the source XLSX used the distorted Latin 'Sal Sedatirum'. Sacred Lotus and Me & Qi both identify the medicinal substance straightforwardly as Borax, the refined borate mineral known in Chinese medicine as Peng Sha.
- Me & Qi preserves the classical saying 'raw form dissolves decay; calcined form regenerates tissue,' capturing the traditional distinction between unprocessed and calcined Peng Sha.
- Historical context recorded by Me & Qi places Peng Sha in the Ri Hua Zi Ben Cao tradition, with later materia medica expanding its use in throat, mouth, ophthalmic, and selected phlegm-heat disorders.
Modern Research
Active Compounds
- Sodium tetraborate decahydrate (hydrated sodium borate mineral) - the principal chemical identity of medicinal borax
- Borate ions (boron-containing inorganic species) - the reactive boron fraction underlying much of borax chemistry
- Boric acid (boron compound formed in aqueous and biologic contexts) - the most commonly studied topical boron species in modern biomedical literature relevant to Peng Sha
- Sodium ions (electrolyte component) - contribute to the mineral's chemical behavior and systemic load in internal exposure
Studied Effects
- Toxicology review literature emphasizes that boric acid, borax, and related boron compounds have clear dose-dependent toxicity, with reproductive and renal safety concerns dominating modern risk assessment rather than routine internal medicinal use (PMID 33485927)
- Periodontal anti-inflammatory activity - boric acid reduced alveolar bone loss while diminishing bone resorption and supporting osteoblast activity in rat periodontitis models, offering a modern correlate to Peng Sha's traditional use in inflamed oral tissues (PMID 33505614)
- Gingival inflammation modulation - boric acid reduced inflammatory signaling and oxidative stress responses in IL-1beta-stimulated human gingival fibroblasts, supporting continued research in oral inflammatory disease (PMID 38692230)
- Wound-healing review literature summarizes antimicrobial, anti-inflammatory, antioxidant, and tissue-regenerative actions across boron compounds, explaining why topical borate preparations continue to attract interest in chronic wound care (PMID 39539690)
PubMed References
Safety & Interactions
Contraindications
- Pregnancy
- Breastfeeding when internal use is being considered
- Liver or kidney impairment
- Long-term internal use
- Yin deficiency with marked dryness or fluid depletion
Cautions
- Peng Sha is a slightly toxic borate mineral best reserved for external use or strictly supervised short-term internal use in powder or pill form only
- Reported adult toxic oral exposure begins in the low-gram range, and infant toxicity thresholds are much lower
- Only refined medicinal-grade borax should be used; industrial borax may carry impurity and heavy-metal risks
- No Memorial Sloan Kettering herb page was found, so this record does not assign herb-drug interactions beyond established toxicology concerns