Black Soybean — Safety & Interactions
Hei Dou · Sojae Semen Nigrum
Use with caution. Practitioner review recommended before use.
Contraindications
- Known soy allergy or hypersensitivity
- Marked bloating or impaired digestion aggravated by beans and legumes
Cautions
- Hei Dou is generally food-grade and mild, but concentrated soy supplements are not equivalent to ordinary culinary amounts
- Large or concentrated soy intake may not be appropriate in every hormone-sensitive context, especially when used as supplement-style extracts rather than food
Drug Interactions
| Drug Class / Substrate | Mechanism | Severity | Source |
|---|---|---|---|
| Tamoxifen | Soy isoflavones such as genistein may antagonize tamoxifen effects on estrogen-dependent breast cancer | Moderate | Memorial Sloan Kettering Integrative Medicine - Soy |
| Aromatase inhibitors | Soy-based supplements may affect treatment efficacy through estrogen-related and aromatase-related signaling | Moderate | Memorial Sloan Kettering Integrative Medicine - Soy |
| Levothyroxine | Case reports suggest soy products may interfere with levothyroxine absorption | Moderate | Memorial Sloan Kettering Integrative Medicine - Soy |
This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before using herbal medicines, especially if you take prescription medications.