Asiatic Pennywort Herb — Safety & Interactions
Ji Xue Cao · Herba Centellae
Use with caution. Practitioner review recommended before use.
Contraindications
- Spleen and Stomach deficiency-cold with loose stools or poor appetite
- Cold-pattern dysmenorrhea or menstruation with marked Cold signs
Cautions
- High doses or prolonged use may cause digestive upset or contribute to liver irritation in susceptible patients
- Use with caution in patients with existing liver disease or when combining with other potentially hepatotoxic supplements
Drug Interactions
| Drug Class / Substrate | Mechanism | Severity | Source |
|---|---|---|---|
| CYP450 substrate drugs | In vitro gotu kola inhibits CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 and may alter intracellular concentrations of substrate drugs | Moderate | Memorial Sloan Kettering Integrative Medicine — Gotu Kola |
This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before using herbal medicines, especially if you take prescription medications.